List of 1721 Major News Events in History, Most Important Historical Events in 1721
| Date | Event |
|---|---|
| January 6, 1721 | The Committee of Inquiry on the South Sea Bubble publishes its findings, revealing details of fraud among company directors and corrupt politicians. |
| March 24, 1721 | Johann Sebastian Bach dedicated six concertos to Margrave Christian Ludwig of Brandenburg-Schwedt, now commonly called the Brandenburg Concertos, BWV 1046 |
| April 3, 1721 | Robert Walpole becomes, in effect, the first Prime Minister of Great Britain, though he himself denied that title. |
| April 26, 1721 | A massive earthquake devastates the Iranian city of Tabriz. |
| August 18, 1721 | The city of Shamakhi in Safavid Shirvan is sacked.[7] |
| August 30, 1721 | The Great Northern War between Sweden and Russia ends in the Treaty of Nystad. |
| October 22, 1721 | The Russian Empire is proclaimed by Tsar Peter I after the Swedish defeat in the Great Northern War. |