List of 1500 Major News Events in History, Most Important Historical Events in 1500
| Date | Event |
|---|---|
| January 1, 1500 | Portuguese explorer Pedro Álvares Cabral discovers the coast of Brazil. |
| February 17, 1500 | Duke Friedrich and Duke Johann attempt to subdue the peasantry of Dithmarschen, Denmark, in the Battle of Hemmingstedt. |
| March 9, 1500 | The fleet of Pedro Álvares Cabral leaves Lisbon for the Indies. The fleet will discover Brazil which lies within boundaries granted to Portugal in the Treaty of Tordesillas in 1494. |
| March 29, 1500 | Cesare Borgia is given the title of Captain General and Gonfalonier by his father Rodrigo Borgia after returning from his conquests in the Romagna. |
| April 10, 1500 | Ludovico Sforza is captured by Swiss troops at Novara and is handed over to the French. |
| April 22, 1500 | Portuguese navigator Pedro Álvares Cabral lands in Brazil. |
| April 23, 1500 | Portuguese explorer Pedro Alvarez Cabral reaches new coastline (Brazil). |
| August 9, 1500 | Ottoman–Venetian War (1499–1503): The Ottomans capture Methoni, Messenia. |
| November 11, 1500 | Treaty of Granada: Louis XII of France and Ferdinand II of Aragon agree to divide the Kingdom of Naples between them. |
| December 24, 1500 | A joint Venetian–Spanish fleet captures the Castle of St. George on the island of Cephalonia. |